Passa al contenuto
MilliporeSigma

Antihypertensive properties of tilapia (

Food & nutrition research (2017-11-21)
Hsin-Chieh Lin, Adeola M Alashi, Rotimi E Aluko, Bonnie Sun Pan, Yu-Wei Chang
ABSTRACT

Proteins from tilapia frame and skin can potentially be precursors of antihypertensive peptides according to the result of BIOPEP analyses. The aim was to generate peptides with inhibitory effects against angiotensin-converting enzyme (ACE) and renin from tilapia frame and skin protein isolates (FPI and SPI). The most active hydrolysate was then tested for blood pressure-lowering ability in spontaneously hypertensive rats (SHRs). Tilapia frame and skin protein hydrolysates (FPHs and SPHs) were respectively produced from FPI and SPI hydrolysis using pepsin, papain, or bromelain. The ACE-inhibitory activities of tilapia protein hydrolysates with varying degree of hydrolysis (DH) were evaluated. In order to enhance the activity, the hydrolysate was fractionated into four fractions (<1 kDa, 1-3 kDa, 3-5 kDa, and 5-10 kDa) and the one with the greatest ability to inhibit

MATERIALI
N° Catalogo
Marchio
Descrizione del prodotto

Sigma-Aldrich
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly
Prezzi e disponibilità al momento non sono disponibili