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  • Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery.

Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery.

Small (Weinheim an der Bergstrasse, Germany) (2015-02-06)
Yannan Yang, Yuting Niu, Jun Zhang, Anand Kumar Meka, Hongwei Zhang, Chun Xu, Chun Xiang Cynthia Lin, Meihua Yu, Chengzhong Yu
ABSTRACT

Large pore (4.6-7.6 nm) and well-dispersed benzene bridged mesoporous organosilica nanoparticles with uniform particle size of ≈50 nm are prepared via a biphasic approach. They can be directly used as nanocarriers without surface modification for the intracellular delivery of therapeutic proteins.

MATERIALI
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Sigma-Aldrich
DAPI, for nucleic acid staining
Sigma-Aldrich
2-Propanolo, for molecular biology, BioReagent, ≥99.5%
Sigma-Aldrich
Trietanolammina, ≥99.0% (GC)
Sigma-Aldrich
2-Propanolo, ≥99.7%, FCC, FG
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2-Propanolo, anhydrous, 99.5%
Sigma-Aldrich
2-Propanolo, BioUltra, for molecular biology, ≥99.5% (GC)
Sigma-Aldrich
2-Propanolo, electronic grade, 99.999% trace metals basis
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Trietanolammina, reagent grade, 98%
Sigma-Aldrich
Trietanolammina, puriss., meets analytical specification of NF, ≥99% (GC)
Sigma-Aldrich
Trietanolammina, BioUltra, ≥99.5% (GC)
Sigma-Aldrich
Trietanolammina, puriss. p.a., ≥99% (GC)