- Synthesis and antihyperlipidemic activity of acetylated derivative of ulvan from Ulva pertusa.
Synthesis and antihyperlipidemic activity of acetylated derivative of ulvan from Ulva pertusa.
International journal of biological macromolecules (2011-11-26)
Huimin Qi, Xiaolei Liu, Jinbao Zhang, Yu Duan, Xiaolan Wang, Quanbin Zhang
PMID22115715
ABSTRACT
In this study, acetylated ulvan (AU) was prepared with acetic anhydride in N,N-dimethylacetamide, and the antihyperlipidemic activity of natural ulvan and its acetylated ulvan derivative (AU) in mice was determined. Obvious differences in antihyperlipidemic activity between natural ulvan and its derivative were observed, moreover, AU showed stronger antihyperlipidemic activity on triglyceride (TG) and low density lipoprotein cholesterol (LDL-C).