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Stereocontrolled access to optically-enriched oxabispidines.

Chemical communications (Cambridge, England) (2012-04-14)
Heloise Brice, Duncan M Gill, Laura Goldie, Philip S Keegan, William J Kerr, Per H Svensson
ABSTRACT

A range of chiral, optically-enriched bicyclic oxabispidines were prepared from (S)-(-)-2,3-epoxypropylphthalimide using an efficient sequence featuring a stereocontrolled intramolecular Mannich reaction as the key transformation.

MATERIALI
N° Catalogo
Marchio
Descrizione del prodotto

Sigma-Aldrich
Phthalimide, ≥99%
Sigma-Aldrich
Phthalimide potassium salt, 98%
Sigma-Aldrich
Phthalimide potassium salt, purum, ≥99.0% (NT)