SRP4869
Placental Lactogen human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)
Sinonimo/i:
CSA, CSH1, CSH2, CSMT, FLJ75407, PL
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About This Item
Prodotti consigliati
Origine biologica
human
Ricombinante
expressed in E. coli
Saggio
≥95% (HPLC)
≥95% (SDS-PAGE)
Forma fisica
lyophilized
PM
~22.3 kDa
Confezionamento
pkg of 20 μg
Condizioni di stoccaggio
avoid repeated freeze/thaw cycles
tecniche
cell based assay: suitable
Impurezze
endotoxin, tested
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
Informazioni sul gene
human ... CSH1(1442)
Descrizione generale
Human placental lactogen (HPL), also called human chorionic somatomammotropin 1, is a polypeptide placental hormone. Its structure and function is similar to that of growth hormone. The gene encoding this protein is localized on human chromosome 17. Recombinant human placental lactogen is a 22.3kDa protein.
Azioni biochim/fisiol
Human placental lactogen (HPL) modifies the metabolic state of the mother during pregnancy to facilitate the energy supply, glucose supply and growth of the fetus. Studies show that targeted expression of this protein in transgenic mice lead to an increase in proliferation of β-cells.
Stato fisico
Sterile filtered and lyophilized with no additives.
Ricostituzione
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.
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PLoS ONE, 9(1), e87325-e87325 (2014)
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The liver increases its size during pregnancy to adapt to metabolic demand associated with pregnancy. Our previous study showed that proliferation of maternal hepatocytes are increased during pregnancy in mice and that estradiol (E2) is one of the candidate hormones
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