G7384

Gallic acid

97.5-102.5% (titration)

• Sinonimo/i: 3,4,5-Trihydroxybenzoic acid
• Formula condensata: (HO)₃C₆H₂CO₂H
• Numero CAS: 149-91-7
• Peso molecolare: 170.12
• Beilstein: 2050274
• Numero CE: 205-749-9
• Numero MDL: MFCD00002510
• Codice UNSPSC: 12352205
• ID PubChem: 24895304
• NACRES: NA.25

Proprietà

• Origine biologica: plant fruit
• Saggio: 97.5-102.5% (titration)
• Forma fisica: powder
• tecniche: HPLC: suitable
• Colore: white to beige
• Punto di fusione: 251 °C (dec.) (lit.)
• Solubilità: ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• Compatibilità: suitable for UV spectrophotometry and general use; suitable for absorption spectrum analysis
• applicazioni: agriculture; metabolomics; microbiology; vitamins, nutraceuticals, and natural products; vitamins, nutraceuticals, and natural products
• Stringa SMILE: OC(=O)c1cc(O)c(O)c(O)c1
• InChI: 1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12); LNTHITQWFMADLM-UHFFFAOYSA-N

Descrizione

Descrizione generale

Gallic acid, also known as 3,4,5-Trihydroxybenzoic acid, is a natural polyhydroxyphenolic compound commonly found in many fruits and plants, including grapes, tea, and oak bark, either in the free acid form or esterified as gallotannins and ellagitannins. Existing research suggests that this plant-derived metabolite is an astringent, a cyclooxygenase-2 (COX-2) and histone acetyltransferase inhibitor, and an apoptosis inducer with various biological activities. These activities include antioxidant, antifungal, gastroprotective, neuroprotective, cardioprotective, antimicrobial, anti-inflammatory, anti-tumor, anti-tyrosinase, and anticancer effects.

Applicazioni

Gallic acid has been used:

• as a standard for the quantification of extractable phenolics by external calibration
• as a standard to determine the total tannin content of oak root powder using the Folin-Ciocalteu method
• as a phenolic acid to study it′s in vitro antiviral, antibacterial, cytotoxicity and antifungal activities

Gallic acid is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Azioni biochim/fisiol

Gallic acid is a water soluble phenolic acid present in grapes and in the leaves of many plants. Gallic acid esters, such as tannins, catechin gallates and aliphatic gallates are potent antioxidants in vitro. However, gallic acid itself also appears to have antioxidant, anticarcinogenic and antiangiogenic activity in vitro.

Caratteristiche e vantaggi

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Altre note

For additional information on our range of Biochemicals, please complete this form.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves