D9315

Deltamethrin

≥98%

• Formula empirica (notazione di Hill): C₂₂H₁₉Br₂NO₃
• Numero CAS: 52918-63-5
• Peso molecolare: 505.20
• Beilstein: 6746312
• Numero CE: 258-256-6
• Numero MDL: MFCD00870122
• Codice UNSPSC: 12352200
• ID PubChem: 24724471
• NACRES: NA.77

Proprietà

• Livello qualitativo: 100
• Saggio: ≥98%
• Forma fisica: solid
• Temperatura di conservazione: −20°C
• Stringa SMILE: CC1(C)[C@@H](\C=C(\Br)Br)[C@H]1C(=O)O[C@H](C#N)c2cccc(Oc3ccccc3)c2
• InChI: 1S/C22H19Br2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17-,18+,20-/m0/s1; OWZREIFADZCYQD-NSHGMRRFSA-N

Descrizione

Applicazioni

Deltamethrin has been used to study its effect:

• as a PP2A/PPP3CA inhibitor by treating HEK293 (human embryonic kidney cells) Tau-BiFC cells
• on the innate immunity in rainbow trout
• on the molecular stress level in black tiger shrimp Penaeus monodon

Azioni biochim/fisiol

Deltamethrin is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B) and has an IC₅₀ of about 100 pM. This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca²⁺ to enter the cell. Some sodium channel mutations such as the L993F mutation in Xenopus oocytes show decreased sensitivity to deltamethrin.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H301 + H331,H410
• Consigli di prudenza: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P311
• Classi di pericolo: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 212.0 °F - closed cup
• Punto d’infiammabilità (°C): 100 °C - closed cup
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges