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Merck
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56962

Sigma-Aldrich

D-myo-Inositol 1,2,4,5,6-pentakis-phosphate

≥96% (HPLC)

Sinonimo/i:

L-myo-Inositol 2,3,4,5,6-pentakis-phosphate

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About This Item

Formula empirica (notazione di Hill):
C6H17O21P5
Numero CAS:
Peso molecolare:
580.06
Numero MDL:
Codice UNSPSC:
12352202
ID PubChem:

Saggio

≥96% (HPLC)

Temperatura di conservazione

−20°C

Stringa SMILE

O[C@H]1[C@@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O

InChI

1S/C6H17O21P5/c7-1-2(23-28(8,9)10)4(25-30(14,15)16)6(27-32(20,21)22)5(26-31(17,18)19)3(1)24-29(11,12)13/h1-7H,(H2,8,9,10)(H2,11,12,13)(H2,14,15,16)(H2,17,18,19)(H2,20,21,22)/t1-,2-,3-,4+,5-,6-/m1/s1
CTPQAXVNYGZUAJ-XCMZKKERSA-N

Azioni biochim/fisiol

Important intermediate in inositol phosphate metabolism. Inositides have an important impact on diverse areas of cellular regulation.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Sean G Jackson et al.
BMC structural biology, 11, 11-11 (2011-02-12)
PH domains represent one of the most common domains in the human proteome. These domains are recognized as important mediators of protein-phosphoinositide and protein-protein interactions. Phosphoinositides are lipid components of the membrane that function as signaling molecules by targeting proteins
Ralf Greiner
The protein journal, 23(8), 577-585 (2005-01-15)
High-pressure liquid chromatography (HPLC) analysis established myo-inositol pentakisphosphate as the final product of phytate dephosphorylation by the phytate-degrading enzyme from Pantoea agglomerans. Neither product inhibition by phosphate nor inactivation of the Pantoea enzyme during the incubation period were responsible for
Nathalie Hayez et al.
Journal of neuroimmunology, 149(1-2), 167-181 (2004-03-17)
The neuropeptides Vasoactive-intestinal peptide (VIP) and Pituitary adenylate-cyclase activating protein (PACAP) increased cAMP levels in three out of five human myeloid leukemic cell lines tested while an increased in calcium intracytoplasmic levels was seen only in one cell line (HEL).
Laura B Sheard et al.
Nature, 468(7322), 400-405 (2010-10-12)
Jasmonates are a family of plant hormones that regulate plant growth, development and responses to stress. The F-box protein CORONATINE INSENSITIVE 1 (COI1) mediates jasmonate signalling by promoting hormone-dependent ubiquitylation and degradation of transcriptional repressor JAZ proteins. Despite its importance
Qingchuan Chen
Journal of agricultural and food chemistry, 52(15), 4604-4613 (2004-07-22)
A high-performance anion exchange chromatographic method was adapted for the quantitative determination of phytic acid and inositol pentakisphosphate isomers (excluding enantiomers) in foods. Because of the cost and limited availability of inositol phosphate standards, a phytic acid sodium salt standard

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