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Merck

SVIL

supervillin

Sinonimi:
Specie:
ID UniProtKB:
ID gene:
  • Human(6840) Summary: This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Jul 2008]
  • Mouse(225115) supervillin
  • Rat(361256) supervillin
  • cow(281509) supervillin
  • dog(477965) supervillin
  • domestic cat(101098723) supervillin
  • domestic guinea pig(100729448) supervillin
  • Horse(100063045) supervillin
  • naked mole-rat(101713658) supervillin
  • chicken(420475) supervillin
  • sheep(101119493) supervillin

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-SVIL antibody produced in mouse, clone 6E10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot
Anti-Supervillin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
immunofluorescence
western blot