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Merck

PBX1

pre-B-cell leukemia homeobox 1

Sinonimi:
Specie:
ID UniProtKB:
ID gene:
  • Human(5087) Summary: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
  • Mouse(18514) pre B cell leukemia homeobox 1
  • Rat(304947) pre-B-cell leukemia homeobox 1
  • cow(540688) pre-B-cell leukemia homeobox 1
  • domestic guinea pig(100723723) pre-B-cell leukemia homeobox 1
  • naked mole-rat(101714961) pre-B-cell leukemia homeobox 1
  • domestic cat(101081781) pre-B-cell leukemia homeobox 1
  • Horse(100058426) pre-B-cell leukemia homeobox 1
  • sheep(101108880) pre-B-cell leukemia homeobox 1
  • dog(488669) pre-B-cell leukemia homeobox 1
  • Domestic Rabbit(100341186) pre-B-cell leukemia homeobox 1
  • chicken(395505) pre-B-cell leukemia homeobox 1

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PBX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-PBX1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-PBX1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human, mouse, rat
Applicazione
ELISA
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Pbx1,
Specie
mouse
MISSION® esiRNA, targeting human PBX1,
Specie
human