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Merck

FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Sinonimi:
CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
Specie:
Human FCGR3A (2214), Rat Fcgr3a (304966), dog FCGR3A (478984), sheep FCGR3A (100192433), cow FCGR3A (281766)
ID UniProtKB:
P08637, A2N6W9, Q53FJ0, Q53FL6, Q5EBR4, Q65ZM6, Q6PIJ0
ID gene:
  • Human(2214) Summary: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(304966) Fc fragment of IgG, low affinity IIIa, receptor
  • dog(478984) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • sheep(100192433) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • cow(281766) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
116R-1
CD16 (SP175) Rabbit Monoclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
ZRB2268
Anti-CD16a Antibody, clone 1E6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
HPA055431
Anti-FCGR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
SAB5500046
Anti-CD16A antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP189, affinity isolated antibody,
Reattività con
human
Applicazione
flow cytometry
immunohistochemistry
western blot
SAB4700709
Monoclonal Anti-CD16-FITC antibody produced in mouse, clone 3G8, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, nonhuman primates
Applicazione
FUNC
flow cytometry
immunohistochemistry
immunoprecipitation (IP)

esiRNA

N° Catalogo
Descrizione
Specie
EHU110711
MISSION® esiRNA, targeting human FCGR3A,
Specie
human