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Merck

F3

coagulation factor III (thromboplastin, tissue factor)

Sinonimi:
CD142, TF, TFA
Specie:
ID UniProtKB:
ID gene:
  • Human(2152) Summary: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(14066) coagulation factor III
  • Rat(25584) coagulation factor III (thromboplastin, tissue factor)
  • naked mole-rat(101702267) coagulation factor III (thromboplastin, tissue factor)
  • domestic guinea pig(100135463) coagulation factor III
  • Domestic Rabbit(100009127) coagulation factor III (thromboplastin, tissue factor)
  • sheep(101118918) coagulation factor III (thromboplastin, tissue factor)
  • cow(280686) coagulation factor III
  • domestic cat(101082330) coagulation factor III (thromboplastin, tissue factor)
  • dog(490153) coagulation factor III (thromboplastin, tissue factor)
  • chicken(429084) coagulation factor III (thromboplastin, tissue factor)

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ELISA

N° Catalogo
Descrizione
Specie
Human F3 / Tissue Factor ELISA Kit, ,
Specie
human
MouseCoagulation Factor III ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie
mouse

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-CD142 PE produced in mouse, ,
Reattività con
human
Applicazione
flow cytometry
Anti-Tissue Factor Antibody, clone 2L10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Tissue Factor/CD142 Antibody, clone HTF-1, ,
Reattività con
bovine, human
Applicazione
ELISA
dot blot

flow cytometry

immunohistochemistry

inhibition assay

western blot
BG8, LewisY (F3) Mouse Monoclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
Monoclonal Anti-CD142 antibody produced in mouse, clone HTF-1,
Reattività con
human
Applicazione
flow cytometry

Proteins

N° Catalogo
Descrizione
Specie
Thromboplastin from rabbit, ,
Specie
domestic rabbit

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human F3,
Specie
human