Passa al contenuto
Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

Sinonimi:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Specie:
Human CHUK (1147), Mouse Chuk (12675), Rat Chuk (309361), Zebrafish chuk (393287), naked mole-rat Chuk (101719306), domestic guinea pig Chuk (100726357), sheep CHUK (101111143), cow CHUK (281073), Horse CHUK (100070393), domestic cat CHUK (101095617) ...Più
ID UniProtKB:
O15111, O14666, Q13132, Q5W0I4, Q92467
ID gene:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
SAB5700523
Anti-Phospho-IKKα/β-S176/180 antibody produced in rabbit, ,
Reattività con
human
Applicazione
western blot
SAB5702171
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
Reattività con
mouse
Applicazione
western blot
SAB4300396
Anti-CHUK (Ab-23) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
ZRB1673
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, feline, human, monkey, mouse, porcine, rat
Applicazione
affinity binding assay
immunohistochemistry
inhibition assay
western blot
MABF222
Anti-IKKa (p45) Antibody, clone 881H3, clone 881H3, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot

Proteins

N° Catalogo
Descrizione
Specie
SRP5040
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
14-461-M
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EMU041031
MISSION® esiRNA, targeting mouse Chuk,
Specie
mouse
EHU229471
MISSION® esiRNA, targeting human CHUK,
Specie
human

Small Molecule - Substrate

N° Catalogo
Descrizione
Specie
12-459
IKK Substrate Peptide, ,
Specie
human