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Merck

CHRNA6

cholinergic receptor, nicotinic, alpha 6 (neuronal)

Sinonimi:
CHNRA6
Specie:
ID UniProtKB:
ID gene:
  • Human(8973) Summary: This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
  • Mouse(11440) cholinergic receptor, nicotinic, alpha polypeptide 6
  • Rat(81721) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic cat(101098219) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • domestic guinea pig(100723150) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • sheep(101119532) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Horse(100049908) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • chicken(396321) cholinergic receptor, nicotinic, alpha 6
  • Zebrafish(555747) cholinergic receptor, nicotinic, alpha 6
  • dog(482836) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • naked mole-rat(101712413) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • cow(539113) cholinergic receptor, nicotinic, alpha 6 (neuronal)
  • Domestic Rabbit(100355656) cholinergic receptor, nicotinic, alpha 6 (neuronal)

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Decamethonium bromide, crystalline,
Specie
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Specie
human, rat

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Mecamylamine hydrochloride, ,
Specie
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Specie
human, rat
Kynurenic acid, ≥98%,
Specie
rat, human

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Tetraethylammonium chloride, ≥98% (titration),
Specie
human
Hexamethonium bromide, ,
Specie
human
Hexamethonium chloride, solid (hygroscopic),
Specie
human
Kynurenic acid, ≥98%,
Specie
rat, human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human CHRNA6,
Specie
human