AIRE
autoimmune regulator
Sinonimi:
AIRE1, APECED, APS1, APSI, PGA1
Specie:
Human AIRE (326), Mouse Aire (11634), Rat Aire (294328), domestic guinea pig Aire (100729880), sheep AIRE (101102698), cow AIRE (784775), Zebrafish aire (100007662), chicken AIRE (429666), dog AIRE (487796), naked mole-rat Aire (101725873)
ID UniProtKB:
ID gene:
- Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
- Rat(294328) autoimmune regulator
- domestic guinea pig(100729880) autoimmune regulator
- sheep(101102698) autoimmune regulator
- cow(784775) autoimmune regulator
- Zebrafish(100007662) autoimmune regulator
- chicken(429666) autoimmune regulator
- dog(487796) autoimmune regulator
- naked mole-rat(101725873) autoimmune regulator
- domestic cat(101091039) autoimmune regulator
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anticorpo anti-AIRE, clone 5H12, clone 5H12, from rat,
Reattività con
mouse
Applicazione
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-AIRE Antibody, clone Mab155, clone Mab155, 1 mg/mL, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-AIRE antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anti-AIRE (Isoform 1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, canine, human, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-AIRE (Isoforms 1 and 2) (AB1) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
ChIP
ELISA
western blot
ELISA
western blot