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  • Evaluation of dry eye and meibomian gland dysfunction after cataract surgery.

Evaluation of dry eye and meibomian gland dysfunction after cataract surgery.

American journal of ophthalmology (2014-02-25)
Kyung Eun Han, Sang Chul Yoon, Ji Min Ahn, Sang Min Nam, R Doyle Stulting, Eung Kweon Kim, Kyoung Yul Seo
ABSTRACT

To evaluate dry eye and meibomian gland dysfunction after cataract surgery. Prospective observational case series. We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). Meibomian gland function may be altered without accompanying structural changes after cataract surgery.

MATERIALS
Product Number
Brand
Product Description

USP
Levofloxacin, United States Pharmacopeia (USP) Reference Standard
Supelco
Levofloxacin, analytical standard
Sigma-Aldrich
Levofloxacin, 98.0-102.0% anhydrous basis (HPLC)