Phosphorescent imaging of living cells using a cyclometalated iridium (III) complex.

Phosphorescent imaging of living cells using a cyclometalated iridium (III) complex.

PloS one (2013-03-05)

Dik-Lung Ma, Hai-Jing Zhong, Wai-Chung Fu, Daniel Shiu-Hin Chan, Hiu-Yee Kwan, Wang-Fun Fong, Lai-Hon Chung, Chun-Yuen Wong, Chung-Hang Leung

PMID23457478

ABSTRACT

A cell permeable cyclometalated iridium(III) complex has been developed as a phosphorescent probe for cell imaging. The iridium(III) solvato complex [Ir(phq)2(H2O]2)] preferentially stains the cytoplasm of both live and dead cells with a bright luminescence.

MATERIALS

Product Number

Brand

Product Description

357324

Sigma-Aldrich

Iridium, foil, thickness 0.25 mm, 99.9% trace metals basis

209686

Sigma-Aldrich

Iridium, powder, 99.9% trace metals basis

449229

Sigma-Aldrich

Iridium, evaporation slug, diam. × L 0.6 cm × 1.2 cm, 99.9% trace metals basis