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  • Morpholine catalyzed direct C3 alkenylation of indoles with α,β-unsaturated aldehydes.

Morpholine catalyzed direct C3 alkenylation of indoles with α,β-unsaturated aldehydes.

Chemical communications (Cambridge, England) (2011-06-21)
Shi-Kai Xiang, Bo Zhang, Li-He Zhang, Yuxin Cui, Ning Jiao
PMID21687862
ABSTRACT

Organocatalytic direct C3 alkenylation of indoles has been developed. Simple and readily available morpholine trifluoroacetic acid salt is employed as an efficient catalyst in this oxidative dehydrogenative reaction. Simplicity and practicality constitute the most attractive advantages of this reaction.

MATERIALS
Product Number
Brand
Product Description
134236
Sigma-Aldrich
Morpholine, ReagentPlus®, ≥99%
Pricing and availability is not currently available.
252360
Sigma-Aldrich
Morpholine, ACS reagent, ≥99.0%
Pricing and availability is not currently available.
394467
Sigma-Aldrich
Morpholine, purified by redistillation, ≥99.5%
Pricing and availability is not currently available.
90179
Supelco
Morpholine, analytical standard
Pricing and availability is not currently available.