SAB5201735

Monoclonal Anti-Tcp1 Alpha - Atto 390 antibody produced in rat

clone 23c, purified immunoglobulin

• Synonym(s): Anti-AI528772, Anti-Ccta, Anti-Tric, Anti-p63
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rat
• Quality Level: 100
• conjugate: Atto 390 conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 23c, monoclonal
• form: buffered aqueous solution
• mol wt: antigen predicted mol wt 60 kDa
• species reactivity: mouse, human, dog, rabbit, rat, hamster, bovine, sheep
• concentration: 1 mg/mL
• technique(s): immunocytochemistry: suitable; immunofluorescence: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG2c
• NCBI accession no.: NP_038714.2
• UniProt accession no.: Q32L40
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Tcp1(21454)

Description

General description

Tcp1 (t-complex protein ) is a chaperonin and a ATPase complex that encodes a chaperonin, localized to the cytosol.

Immunogen

Purified recombinant mouse TCP1 alpha construct encoding the C-terminal half of the 1.8 kb full-length Tcp 1b gene expressed in E. coli. Detects the COOH group.

Biochem/physiol Actions

Tcp1 (t-complex protein) is involved in protein folding mechanism of essential proteins such as actins, tubulin, cyclin E, α-transducin and von Hippel Lindau protein. Tcp1 participates in synthesis of proteins that make up the cytoskeleton and thus involved in cellular processes such as chromosome segregation, cell migration, and intracellular transport. Increased TCP1 gene expression is observed in cancer and upregulation elevates with the disease progression.

Features and Benefits

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Physical form

PBS pH7.4, 50% glycerol, 0.1% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable