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EMU068891

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Abca1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GAACTTTGCCAAGGACCAAAGTGATGATGACCACTTAAAGGACCTGTCACTGCACAAAAACCAGACAGTTGTGGATGTGGCCGTTCTCACATCCTTTTTGCAGGATGAGAAAGTGAAAGAAAGTTATGTATGAAGAATCCCGTTCACACAGGGTGAATGAAAGGAAGGAAGAGCGAGGTCTTCCTTTGCACTGTGTCAAGTGTTCTAGAAGAAAGCGTCCTGCGTTTCTGTGGAGAAGAACAAACTGGATACTGTACTGACACTATTCAATGCAATGCACTTCAATGCAACGAGAACACAATTCCATTACAGGGGCAGTGCCTTTGTAGCCTATGTCTTGTATGGCTCTCTAGTGAAAATGACTTGAAGTTAGTTCATTACCTTATACAGATGTGAAACTCTGGTGTGGAACCAAGCAGACT

Ensembl | mouse accession no.

ENSMUSG00000015243

NCBI accession no.

NM_013454

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... ABCA1(11303) , Abca1(11303)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Li Zhou et al.
PloS one, 4(8), e6853-e6853 (2009-09-01)
ATP-binding cassette transporter A1 mediates apolipoprotein AI-dependent efflux of cholesterol and thereby removes cholesterol from peripheral tissues. ABCA1 expression is tightly regulated and deficiency of this cholesterol transporter results in cholesterol accumulation within cells. Low-density lipoprotein receptor-related protein 1 (LRP1)
Shenshen Zhu et al.
Pharmacology, 95(5-6), 258-263 (2015-05-23)
This study was conducted to explore the effect of zerumbone, isolated from Zingiberzerumbet Smith, on apolipoprotein A-I (apoA-I)-mediated cholesterol efflux from THP-1 macrophages. THP-1 macrophages were treated with different concentrations (10-100 μmol/l) of zerumbone and cholesterol efflux was measured. The

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