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Merck

PDCD10

programmed cell death 10

Synonyms:
CCM3, TFAR15
Species:
UniProtKB ID:
Gene ID:
  • Human(11235) Summary: This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(56426) programmed cell death 10
  • Rat(494345) programmed cell death 10
  • sheep(101122826) programmed cell death 10
  • dog(488145) programmed cell death 10
  • naked mole-rat(101715475) programmed cell death 10
  • cow(506411) programmed cell death 10
  • chicken(425003) programmed cell death 10
  • domestic cat(101090640) programmed cell death 10
  • domestic guinea pig(100729780) programmed cell death 10

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CCM3/PDCD10, from rabbit, purified by affinity chromatography,
Species Reactivity
xenopus, human, mouse, rat
Application
western blot
ANTI-PDCD10 (CENTER) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-PDCD10 antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Anti-PDCD10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PDCD10,
Species
human
MISSION® esiRNA, targeting mouse Pdcd10,
Species
mouse