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Merck

CASP7

caspase 7, apoptosis-related cysteine peptidase

Synonyms:
CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Species:
Human CASP7 (840), Mouse Casp7 (12369), Rat Casp7 (64026), Goat CASP7 (100861343), dog CASP7 (486896), Zebrafish casp7 (553634), chicken CASP7 (423901), naked mole-rat Casp7 (101709568), domestic guinea pig Casp7 (100715159), cow CASP7 (526279) ...More
UniProtKB ID:
P55210, B4DQU7, B5BU45, D3DRB8, Q13364, Q53YD5, Q5SVL0, Q5SVL3
Gene ID:
  • Human(840) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(12369) caspase 7
  • Rat(64026) caspase 7
  • Goat(100861343) caspase 7, apoptosis-related cysteine peptidase
  • dog(486896) caspase 7, apoptosis-related cysteine peptidase
  • Zebrafish(553634) caspase 7, apoptosis-related cysteine peptidase
  • chicken(423901) caspase 7, apoptosis-related cysteine peptidase
  • naked mole-rat(101709568) caspase 7, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715159) caspase 7, apoptosis-related cysteine peptidase
  • cow(526279) caspase 7, apoptosis-related cysteine peptidase
  • sheep(101122741) caspase 7, apoptosis-related cysteine peptidase
  • domestic cat(768262) caspase 7, apoptosis-related cysteine peptidase

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ELISA

Product Number
Description
Species
RAB1314
Human Caspase-7 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB4503314
Anti-CASP7 (Cleaved-Asp198) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
PRS3467
Anti-Caspase-7 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
ZRB1676
Anti-Caspase-7 Antibody, clone 1E21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
flow cytometry
immunohistochemistry
western blot
SAB4503316
Anti-CASP7 (p20, Cleaved-Asp198) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
C1104
Monoclonal Anti-Caspase 7 antibody produced in rat, clone 11E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunoprecipitation (IP)
microarray
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
A0835
N-Acetyl-Asp-Glu-Val-Asp-al, ≥95%, powder,
Species
human
N1413
NSCI, ≥97% (HPLC), solid,
Species
human

esiRNA

Product Number
Description
Species
EHU090761
MISSION® esiRNA, targeting human CASP7,
Species
human