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  • Hypothyroidism-related onycholysis with Aureobasidium pullulans colonization successfully treated with antifungal therapy.

Hypothyroidism-related onycholysis with Aureobasidium pullulans colonization successfully treated with antifungal therapy.

Clinical and experimental dermatology (2012-03-24)
M Arabatzis
ABSTRACT

This is a report, the first to my knowledge, of secondary nail-apparatus involvement by Aureobasidium pullulans in a patient with onycholysis related to hypothyroidism. Complete cure of the lesions was seen after 2 weeks of itraconazole and 2 months of local bifonazole therapy. This case raises concern about the extent of involvement of this yeast in onycholysis of diverse clinical aetiologies.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Bifonazole, ≥98% (HPLC)
Supelco
Bifonazole, Pharmaceutical Secondary Standard; Certified Reference Material
Bifonazole, European Pharmacopoeia (EP) Reference Standard