- First diastereoselective chiral synthesis of (-)-securinine.
First diastereoselective chiral synthesis of (-)-securinine.
Organic letters (2004-01-03)
Toshio Honda, Hidenori Namiki, Kyosuke Kaneda, Hirotake Mizutani
PMID14703357
ABSTRACT
[reaction: see text] A diastereoselective total synthesis of securinine in optically pure form was achieved by employing ring-closing metathesis of the corresponding dienyne compound as a key step.
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