Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation.

Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation.

Molecular diversity (2011-01-06)

Mario O Salazar, Oscar Micheloni, Andrea M Escalante, Ricardo L E Furlan

PMID21207143

ABSTRACT

A semisynthetic β-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step.

MATERIALS

Product Number

Brand

Product Description

108138

Sigma-Aldrich

Benzenesulfonyl chloride, 99%

Pricing and availability is not currently available.

108111

Sigma-Aldrich

Benzenesulfonyl chloride, 96%

Pricing and availability is not currently available.

12620

Sigma-Aldrich

Benzenesulfonyl chloride, for HPLC derivatization

Pricing and availability is not currently available.