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Merck

SIPA1

signal-induced proliferation-associated 1

Synonyms:
SPA1
Species:
UniProtKB ID:
Gene ID:
  • Human(6494) Summary: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]
  • Mouse(20469) signal-induced proliferation associated gene 1
  • Rat(361710) signal-induced proliferation-associated 1
  • domestic guinea pig(100731279) signal-induced proliferation-associated 1
  • naked mole-rat(101717091) signal-induced proliferation-associated 1
  • sheep(101101937) signal-induced proliferation-associated 1
  • domestic cat(101099149) signal-induced proliferation-associated 1
  • dog(483730) signal-induced proliferation-associated 1
  • cow(508234) signal-induced proliferation-associated 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-SIPA1, (C-terminal) antibody produced in mouse, clone 2B4, ascites fluid,
Species Reactivity
human
Application
ELISA
Anti-SPA1/SIPA1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-SIPA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-SIPA1 Antibody, clone 1D5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Sipa1,
Species
mouse
MISSION® esiRNA, targeting human SIPA1,
Species
human