PDGFRB
platelet-derived growth factor receptor, beta polypeptide
Synonyms:
CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1
Species:
Human PDGFRB (5159), Mouse Pdgfrb (18596), Rat Pdgfrb (24629), domestic guinea pig Pdgfrb (100726506), naked mole-rat Pdgfrb (101721151), Zebrafish pdgfrb (559529), chicken PDGFRB (770488), dog PDGFRB (442985), domestic cat PDGFRB (101084600), cow PDGFRB (527165) ...More
UniProtKB ID:
Gene ID:
- Human(5159) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
- Mouse(18596) platelet derived growth factor receptor, beta polypeptide
- Rat(24629) platelet derived growth factor receptor, beta polypeptide
- domestic guinea pig(100726506) platelet-derived growth factor receptor, beta polypeptide
- naked mole-rat(101721151) platelet-derived growth factor receptor, beta polypeptide
- Zebrafish(559529) platelet-derived growth factor receptor beta
- chicken(770488) platelet-derived growth factor receptor, beta polypeptide
- dog(442985) platelet-derived growth factor receptor, beta polypeptide
- domestic cat(101084600) platelet-derived growth factor receptor, beta polypeptide
- cow(527165) platelet-derived growth factor receptor, beta polypeptide
- Domestic Rabbit(100342872) platelet-derived growth factor receptor, beta polypeptide
- sheep(101122783) platelet-derived growth factor receptor, beta polypeptide
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Product Number
Description
Species
Phosphotyrosine PDGFRB / Platelet-derived Growth Factor Receptor Beta ELISA Kit, ,
Species
human
Human PDGF R β ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PDGFR β antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-CD140b antibody produced in mouse, clone 18A2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD140b-PE antibody produced in mouse, clone 18A2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-PDGFRB antibody produced in mouse, clone 4C12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
proximity ligation assay
western blot
immunoprecipitation (IP)
proximity ligation assay
western blot
Anti-PDGFRB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
PDGFRb active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Species
human
PDGFRβ(557-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
PDGFRβ Protein, active, 50 µg, Active, recombinant human PDGF Receptor β, residues 557-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
Species
human
esiRNA
Product Number
Description
Species