NDUFA1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
Synonyms:
CI-MWFE, MWFE, ZNF183
Species:
Human NDUFA1 (4694), Mouse Ndufa1 (54405), Rat Ndufa1 (363441), dog NDUFA1 (481033), domestic cat NDUFA1 (101085609), chicken NDUFA1 (772150), naked mole-rat Ndufa1 (101713738), Zebrafish ndufa1 (415243), cow NDUFA1 (327673), sheep NDUFA1 (100216464)
UniProtKB ID:
Gene ID:
- Human(4694) Summary: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008]
- Mouse(54405) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
- Rat(363441) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
- dog(481033) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- domestic cat(101085609) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- chicken(772150) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- naked mole-rat(101713738) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- Zebrafish(415243) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
- cow(327673) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
- sheep(100216464) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 3B9-1A1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Monoclonal Anti-NDUFA1 antibody produced in mouse, clone 2A4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-NDUFA1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-NDUFA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Small Molecule - Inhibitor
Product Number
Description
Species
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
esiRNA
Product Number
Description
Species