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Merck

HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(3158) Summary: The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(15360) 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
  • Rat(24450) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • domestic guinea pig(100727078) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • chicken(424380) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • Domestic Rabbit(100343479) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • cow(503684) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • domestic cat(101088768) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • dog(607923) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • Goat(100860890) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • Horse(100059971) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • sheep(101111590) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
  • naked mole-rat(101712063) 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-HMGCS2, (C-terminal) antibody produced in mouse, clone 1E9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-HMGCS2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-HMGCS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-HMGCS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-HMGCS2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human HMGCS2,
Species
human
MISSION® esiRNA, targeting mouse Hmgcs2,
Species
mouse