CBX1
chromobox homolog 1
Synonyms:
CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta
Species:
Human CBX1 (10951), Mouse Cbx1 (12412), Rat Cbx1 (360609), domestic cat CBX1 (101084070), cow CBX1 (616506), chicken CBX1 (374237), naked mole-rat Cbx1 (101706928), dog CBX1 (491051), domestic guinea pig Cbx1 (100716439), sheep CBX1 (101116158)
UniProtKB ID:
Gene ID:
- Human(10951) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(12412) chromobox 1
- Rat(360609) chromobox homolog 1
- domestic cat(101084070) chromobox homolog 1
- cow(616506) chromobox homolog 1
- chicken(374237) chromobox homolog 1
- naked mole-rat(101706928) chromobox homolog 1
- dog(491051) chromobox homolog 1
- domestic guinea pig(100716439) chromobox homolog 1
- sheep(101116158) chromobox homolog 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CBX1/HP1-β antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CBX1 antibody produced in mouse, clone 4E12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CBX1 Antibody, clone 1D7 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-Heterochromatin Protein-1 β Antibody, clone 1MOD-1A9, ascites fluid, clone 1MOD-1A9, Chemicon®,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-CBX1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat, yeast
Application
western blot
esiRNA
Product Number
Description
Species