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Get in the Fast Lane – Vital Products at Starting Line

A curated selection of essential biotech technologies and expert advice to start your process development

Accelerate your path to the patient with a curated set of technologies and expert counsel

Whether you are in the early stages of developing monoclonal antibodies, cell therapies, or gene therapies, you need to establish a robust and scalable GMP production process.

Selecting the right technologies is essential but can be time-consuming and resource-intensive with so many choices and variables to consider. Choose the right solutions at the starting line and you’ll establish a workflow that positions you for long-term success, reduces risk, and accelerates progress towards your most important milestones.

Get a headstart! Talk to our team of experts today.

We invite you to explore these proven upstream, downstream, and final fill/formulation manufacturing technologies and then connect with our experts to tailor the perfect set for your specific process requirements.

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Gene Therapies Technologies & Solutions

Gene therapy offers tremendous potential to treat and cure countless diseases for which there is a high unmet need. And require critical speed to market to meet patient needs.

While development and production require speed and agility, gene therapies are manufactured without any templated approach, under evolving regulatory guidelines, and in many cases, for small patient populations.

Process efficiency, scalability, and high costs are just a few of the challenges facing the industry as innovators seek to maximize productivity, purity, and yield.

Explore our technologies, products, and services design to overcome these challenges and support the gene therapy manufacturing workflow from process development to commercial-scale productions. 

Take the first step today! Talk to our team of experts.

Illustration of an adeno-associated virus

AAV Vector Production

Adeno-associated viruses (AAV) are an important component of many in vivo gene therapies, where they deliver essential genetic material to various cells and tissues.

Find the products we recommend to start your AAV process development. 

Interested into our full capabilities for your AAV process? Browse the Biopharmaceutical Application Guide  to help you find the right products and services for your needs.

 

Illustration of a lentiviral vector

Lentivirus Production

Lentiviral vectors are primarily used in ex vivo gene therapy to transport new genetic material into cells cultured outside of the body, which are then administered to the patient.

Interested into our full capabilities for your Lentivirus process? Browse the Biopharmaceutical Application Guide  to help you find the right products and services for your needs.

 

Illustration of a monoclonal antibody

mAbs Production

Monoclonal antibodies (mAb) are manufactured using a templated approach that encompasses all steps in the process from cell line development to final fill.  Despite the process being templated, robust and scalable solutions are essential to meet productivity, yield, and purity objectives. Additional initiatives include increasing upstream bioreactor titers, formulating high therapeutic concentrations, and adopting continuous processes.

Explore our technologies, products and services that support your mAb programs from process development to commercial scale and help deliver on your productivity objectives and initiatives.

Interested into our full capabilities for your Monoclonal Antibody process? Browse the Biopharmaceutical Application Guide  to help you find the right products and services for your needs.

 

Talk to One of our Experts Today

Related Applications
PAT: Build Quality into Biopharmaceutical Processes with Real-Time Monitoring and Control
Process Analytical Technology (PAT) ensures quality in biopharmaceutical manufacturing by monitoring and controlling processes in real-time. It utilizes analytical tools to develop manufacturing processes that accommodate material and equipment variability.
Related Product Categories
Bioprocessing Cell Lines
Our ready-to-use, off-the-shelf cell line systems greatly reduce the time, cost, and risk of developing new cell lines for production. Whether you are producing antibodies, recombinant proteins, or viral vectors for gene therapies, our cell line platforms can accelerate your upstream progress.
Bioprocessing Cell Culture Media
Our off-the-shelf and customizable bioprocessing cell culture media (CCM) products enhance productivity in upstream mAb, vaccine, gene/cell therapy processes.
Bioprocessing Mobius® Single-Use Bioreactors
The Mobius® Bioreactor family includes the bench scale (2 mL and 3 L), pilot, clinical and commercial manufacturing (50 – 2,000 L) single-use bioreactors that enable cell culturing capabilities from early process development through commercial batch production.
Clarification Depth Filters & Pretreatment Solutions
Elevate your cell culture process: Employ Millistak+® and Clarisolve® filters for efficient upstream clarification and secondary polishing.
Affinity Chromatography Resins
Affinity chromatography is often used during the capture phase to isolate the target molecule and reduce process volume. Our range of affinity resins includes Protein A, anti-A and anti-B, and metal chelate resin, designed for high throughput and cost-effective purification.
Membrane Chromatography
Optimize downstream purification using membrane chromatography for capture and polishing. Natrix membranes boost economics and facility efficiency.
Ion Exchange Chromatography Resins
Ion exchange (IEX) chromatography separates biomolecules based on the difference in charge between the target molecule and chromatography resin.
Tangential Flow Filtration Devices
Elevate Filtration Precision: Our tangential flow products ensure purity for mAbs, vaccines, and more, scaling from single-use to multi-use.
Related Services
Emprove® Program
Emprove® Program: The smart way to master compliance and control. Complementing our product portfolio, the Emprove® Program provides convenient access to reliable technical, regulatory and supply information in Emprove® Dossiers to support your risk assessment continuum.
Cell and Viral Bank Testing
Cell and viral bank testing is an important part of a robust viral detection strategy. We partner with you to conduct a risk assessment and develop strategies for cell line characterization and genetic stability studies.
mAb Product Characterization
When moving your monoclonal antibody (mAb) from concept to clinic, our product characterization services and assay packages help ensure your biotherapy’s safety, purity, and potency while expediting quality decisions at every stage.
Analytical Development and Characterization for Adeno-Associated Virus (AAV)
Our phase-appropriate analytical development and method validation capabilities provide the product and process knowledge you need to develop a Quality Target Product Profile and identify the Critical Quality Attributes for your AAV therapy.
Viral Vector Contract Testing, Development, & Manufacturing Services (CTDMO)
Millipore® CTDMO Services delivers expertise and flexible solutions for viral vector development and manufacturing to advance cell and gene therapies from preclinical through commercial production. Our proficiency with adeno-associated virus (AAV), lentivirus, adenovirus, and other vectors helps streamline the development and manufacturing.
mAb Development and Manufacturing Services
With Millipore® CTDMO Services we provide deep expertise and flexible solutions across all stages of development and manufacturing for monoclonal antibodies, bi-specific antibodies, fusion proteins, or antibody fragments. From mammalian cell line and process development to media and feed screening, master cell banking, scale-up, and GMP clinical and commercial drug substance.
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