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  • Room-temperature Suzuki-Miyaura couplings in water facilitated by nonionic amphiphiles.

Room-temperature Suzuki-Miyaura couplings in water facilitated by nonionic amphiphiles.

Organic letters (2008-03-14)
Bruce H Lipshutz, Tue B Petersen, Alexander R Abela
ABSTRACT

Use of a dilute aqueous solution containing a nonionic amphiphile allows efficient Suzuki-Miyaura cross-couplings of arylboronic acids with a wide array of aryl halides and pseudohalides, including sterically hindered and lipophilic substrates, in most cases at room temperature.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
[1,1′-Bis(di-tert-butylphosphino)ferrocene]dichloropalladium(II), 98%
Sigma-Aldrich
CX31, Umicore, 95%