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Merck

TAF6L

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

Synonyms:
PAF65A
Species:
UniProtKB ID:
Gene ID:
  • Human(10629) Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. [provided by RefSeq, Jul 2008]
  • Mouse(225895) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
  • Rat(309194) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
  • Zebrafish(557363) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
  • cow(531109) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • domestic cat(101088188) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • dog(476051) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • sheep(101112524) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • naked mole-rat(101698270) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
  • domestic guinea pig(100733115) TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TAF6L antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-TAF6L Antibody, clone 1M8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, porcine, rat
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-TAF6L antibody produced in mouse, clone 1C5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-TAF6L antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-TAF6L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Taf6l,
Species
mouse
MISSION® esiRNA, targeting human TAF6L,
Species
human