SPRY2
sprouty homolog 2 (Drosophila)
Synonyms:
hSPRY2
Species:
Human SPRY2 (10253), Mouse Spry2 (24064), Rat Spry2 (306141), chicken SPRY2 (395584), domestic guinea pig Spry2 (100729578), naked mole-rat Spry2 (101706722), dog SPRY2 (485504), Horse SPRY2 (100050086), domestic cat SPRY2 (101088453), cow SPRY2 (539090)
UniProtKB ID:
Gene ID:
- Human(10253) Summary: This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
- Mouse(24064) sprouty homolog 2 (Drosophila)
- Rat(306141) sprouty homolog 2 (Drosophila)
- chicken(395584) sprouty homolog 2 (Drosophila)
- domestic guinea pig(100729578) sprouty homolog 2 (Drosophila)
- naked mole-rat(101706722) sprouty homolog 2 (Drosophila)
- dog(485504) sprouty homolog 2 (Drosophila)
- Horse(100050086) sprouty homolog 2 (Drosophila)
- domestic cat(101088453) sprouty homolog 2 (Drosophila)
- cow(539090) sprouty homolog 2 (Drosophila)
- Zebrafish(335098) sprouty homolog 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Spry2 Antibody, Upstate®, from rabbit,
Species Reactivity
human, rat
Application
western blot
Anti-Sprouty 2 (N-Terminal) from rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Sprouty 2 Antibody, clone 10M8H1, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Anti-SPRY2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, human, mouse, pig, rat
Application
immunohistochemistry
western blot
western blot
Anti-SPRY2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence