SMOX
spermine oxidase
Synonyms:
C20orf16, PAO, PAO-1, PAOH1, SMO
Species:
Human SMOX (54498), Mouse Smox (228608), Rat Smox (308652), Horse SMOX (100052311), naked mole-rat Smox (101707899), cow SMOX (527211), dog SMOX (485787), domestic guinea pig Smox (100715262), Zebrafish smox (387290), chicken SMOX (422934) ...More
UniProtKB ID:
Gene ID:
- Human(54498) Summary: Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012]
- Mouse(228608) spermine oxidase
- Rat(308652) spermine oxidase
- Horse(100052311) spermine oxidase
- naked mole-rat(101707899) spermine oxidase
- cow(527211) spermine oxidase
- dog(485787) spermine oxidase
- domestic guinea pig(100715262) spermine oxidase
- Zebrafish(387290) spermine oxidase
- chicken(422934) spermine oxidase
- Domestic Rabbit(100347645) spermine oxidase
- domestic cat(101084867) spermine oxidase
- sheep(101118975) spermine oxidase
- fruit fly(31738) Smad on X
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SMOX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-SMOX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-SMOX (151-165) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot