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Merck

OGT

O-linked N-acetylglucosamine (GlcNAc) transferase

Synonyms:
HRNT1, O-GLCNAC
Species:
UniProtKB ID:
Gene ID:
  • Human(8473) Summary: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(108155) O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
  • Rat(26295) O-linked N-acetylglucosamine (GlcNAc) transferase
  • domestic cat(101094162) O-linked N-acetylglucosamine (GlcNAc) transferase
  • dog(480955) O-linked N-acetylglucosamine (GlcNAc) transferase
  • chicken(422203) O-linked N-acetylglucosamine (GlcNAc) transferase
  • sheep(101106996) O-linked N-acetylglucosamine (GlcNAc) transferase
  • cow(532053) O-linked N-acetylglucosamine (GlcNAc) transferase
  • Horse(100056148) O-linked N-acetylglucosamine (GlcNAc) transferase
  • Domestic Rabbit(100354727) O-linked N-acetylglucosamine (GlcNAc) transferase
  • domestic guinea pig(100728617) O-linked N-acetylglucosamine (GlcNAc) transferase

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-OGT antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
western blot
Anti-β-O-Linked N-Acetylglucosamine antibody, Mouse monoclonal, clone CTD110.6, purified from hybridoma cell culture,
Species Reactivity
wide range
Application
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-OGT, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-O-GlcNAc antibody produced in mouse, clone 9H6,
Species Reactivity
human
Application
immunofluorescence
western blot
Monoclonal Anti-O-GlcNAc-R-Phycoerythrin antibody produced in mouse, clone 9H6,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human OGT,
Species
human
MISSION® esiRNA, targeting mouse Ogt,
Species
mouse