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Merck

NEFH

neurofilament, heavy polypeptide

Synonyms:
NFH
Species:
UniProtKB ID:
Gene ID:
  • Human(4744) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
  • Mouse(380684) neurofilament, heavy polypeptide
  • Rat(24587) neurofilament, heavy polypeptide
  • chicken(417020) neurofilament, heavy polypeptide
  • domestic cat(101087272) neurofilament, heavy polypeptide
  • naked mole-rat(101704170) neurofilament, heavy polypeptide
  • domestic guinea pig(100716406) neurofilament, heavy polypeptide
  • sheep(101107472) neurofilament, heavy polypeptide
  • cow(528842) neurofilament, heavy polypeptide
  • dog(442940) neurofilament, heavy polypeptide

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Neurofilament H, purified produced in mouse, ,
Species Reactivity
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-NEFH antibody produced in mouse, clone 2E8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-Neurofilament 200 antibody produced in mouse, clone NE14, ascites fluid,
Species Reactivity
bovine, chicken, guinea pig, human, mouse, pig, rabbit, rat
Application
immunohistochemistry
microarray

western blot
Anti-NEFH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-Neurofilament 200 (Phos and Non-Phos) antibody, Mouse monoclonal, clone N52, purified from hybridoma cell culture,
Species Reactivity
bovine, feline, human, monkey, mouse, pig, rat
Application
immunofluorescence
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NEFH,
Species
human