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Merck

IL2RA

interleukin 2 receptor, alpha

Synonyms:
CD25, IDDM10, IL2R, TCGFR
Species:
UniProtKB ID:
Gene ID:
  • Human(3559) Summary: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
  • Mouse(16184) interleukin 2 receptor, alpha chain
  • Rat(25704) interleukin 2 receptor, alpha
  • dog(403870) interleukin 2 receptor, alpha
  • chicken(395294) interleukin 2 receptor, alpha
  • cow(281861) interleukin 2 receptor, alpha
  • Horse(100070292) interleukin 2 receptor, alpha
  • domestic cat(493953) interleukin 2 receptor, alpha
  • domestic guinea pig(100715332) interleukin 2 receptor, alpha
  • sheep(443435) interleukin 2 receptor, alpha
  • naked mole-rat(101696651) interleukin 2 receptor, alpha

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  • Custom Gene Products

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ELISA

Product Number
Description
Species
Mouse Il2Ra / Interleukin-2 Receptor Subunit Alpha ELISA Kit, ,
Species
mouse
Human IL2RA / Interleukin-2 Receptor Subunit Beta ELISA Kit, ,
Species
human
Human IL2RA / Interleukin-2 Receptor Subunit Alpha ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human
Rat IL-2 R alpha ELISA, for serum, plasma and cell culture supernatants,
Species
rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD25 PE-Cyanine7 produced in mouse, ,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD25-PE antibody produced in mouse, clone MEM-181, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-CD25 Antibody (mouse), APC, clone PC61.5, clone PC61.5, 0.2 mg/mL, from rat,
Species Reactivity
mouse
Application
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
CD25 (4C9) Mouse Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Anti-CD25 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP176, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Interleukin-2 Soluble Receptor α human, >97% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL2RA,
Species
human