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Merck

CAD

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(790) Summary: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. [provided by RefSeq, Jul 2008]
  • Mouse(69719) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • Rat(24240) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • fruit fly(35341) caudal
  • Zebrafish(266992) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • chicken(428659) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • dog(483009) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • domestic cat(101091102) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • Horse(100055366) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • cow(504261) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • sheep(101115776) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • Domestic Rabbit(100352236) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • domestic guinea pig(100727133) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
  • naked mole-rat(101710382) carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Cad Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-CAD Antibody, clone 0O8D6, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-CAD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-CAD antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CAD,
Species
human
MISSION® esiRNA, targeting mouse Cad,
Species
mouse