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Merck

B4GALT4

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

Synonyms:
B4Gal-T4, beta4Gal-T4
Species:
UniProtKB ID:
Gene ID:
  • Human(8702) Summary: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56375) UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
  • Rat(303923) UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
  • domestic guinea pig(100735550) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
  • dog(608143) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
  • naked mole-rat(101723638) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
  • domestic cat(101100325) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
  • cow(511328) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
  • sheep(101104949) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
  • Zebrafish(492760) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
  • chicken(418341) UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-B4GALT4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-B4GALT4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-B4GALT4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-B4GALT4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human B4GALT4,
Species
human
MISSION® esiRNA, targeting mouse B4galt4,
Species
mouse