Skip to Content
Merck

AIMP1

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Synonyms:
EMAP2, EMAPII, HLD3, SCYE1, p43
Species:
UniProtKB ID:
Gene ID:
  • Human(9255) Summary: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]
  • Mouse(13722) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • Rat(114632) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • cow(505126) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • domestic cat(101084875) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • domestic guinea pig(100735088) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • naked mole-rat(101716714) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • chicken(422533) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • Domestic Rabbit(100009367) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • Zebrafish(562232) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • dog(487893) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
  • sheep(101121350) aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-EMAPII Antibody, clone M7/1, (Preservat ive free), clone M7/1, from rat,
Species Reactivity
human, mouse
Application
activity assay
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Aimp1,
Species
mouse
MISSION® esiRNA, targeting human AIMP1,
Species
human