- Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters.
Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters.
Chemical communications (Cambridge, England) (2013-03-15)
Aiichiro Nagaki, Daisuke Ichinari, Jun-ichi Yoshida
PMID23486774
ABSTRACT
Reactions of functionalized aryllithiums with dialkyl oxalates were achieved using a flow microreactor to obtain α-keto esters with high selectivity by virtue of fast 1 : 1 micromixing.