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Mechanisms of Specific Embryonic Effects of Nitrogen Oxide.

Bulletin of experimental biology and medicine (2018-09-19)
A M Dolgorukova, V Yu Titov, V A Petrov, A N Osipov, N A Slesarenko, I I Kochish
ABSTRACT

The study of NO metabolism in chicken embryos showed that the intensity of oxidation of both endogenous and exogenous for the embryo NO donors to nitrate is determined by the presence or state of NO targets, rather than donor concentration. The mechanism of this oxidation and its physiological role are discussed. It was also shown that oxidation product nitrate is actively eliminated from the amnionic sac.

MATERIALS
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Sigma-Aldrich
Vanadium(III) chloride, 97%