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Key Documents

SRP0302

Sigma-Aldrich

HDAC10 FLAG tag active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥38% (SDS-PAGE)

Synonym(s):

HD10, histone deacetylase 10

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥38% (SDS-PAGE)

form

aqueous solution

mol wt

67 kDa

packaging

pkg of 50 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... HDAC10(83933)

General description

Human HDAC10 (GenBank Accession No. NM_032019), amino acids 2-631 with N-terminal FLAG-tag, MW= 67 kDa, expressed in Sf9 cells via a Baculovirus expression system.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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W Fischle et al.
The Journal of biological chemistry, 276(38), 35826-35835 (2001-07-24)
Histone deacetylases (HDACs) are part of transcriptional corepressor complexes and play key roles in regulating chromatin structure. Three different classes of human HDACs have been defined based on their homology to HDACs found in Saccharomyces cerevisiae: RPD3 (class I), HDA1
Sharmistha Chakraborty et al.
The Journal of biological chemistry, 281(46), 35070-35080 (2006-09-19)
Histone deacetylase 7 (HDAC7) is a member of class IIa HDACs that regulate myocyte enhancer factor-2 (MEF2)-mediated transcription and participate in multiple cellular processes such as T cell apoptosis. We have identified alpha-actinin 1 and 4 as class IIa HDAC-interacting

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