SML1389

Farrerol

≥98% (HPLC)

• Synonym(s): (-)-Farrerol, (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethyl-4-benzopyrone, 4′,5,7-Trihydroxy 6,8-dimethylflavanone, CID 442396
• Empirical Formula (Hill Notation): C₁₇H₁₆O₅
• CAS Number: 24211-30-1
• Molecular Weight: 300.31
• EC Number: 246-080-2
• MDL number: MFCD28347824
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825837
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: CC1=C(O)C(C)=C(O)C2=C1O[C@H](C3=CC=C(O)C=C3)CC2=O
• InChI: 1S/C17H16O5/c1-8-15(20)9(2)17-14(16(8)21)12(19)7-13(22-17)10-3-5-11(18)6-4-10/h3-6,13,18,20-21H,7H2,1-2H3/t13-/m0/s1
• InChI key: DYHOLQACRGJEHX-ZDUSSCGKSA-N

Description

Biochem/physiol Actions

Farrerol is major bioactive component from Rhododendron dauricum L. (Man-Shan-Hong). Farrerol exhibits numerous activities including antibechic, anti-bacterial, anti-inflammatory and inhibition of vascular smooth muscle cells (VSMC) proliferation. Recent study shows that Farrerol regulates occludin expression by preventing H2O2-induced activation ERK 1/2 in human endothelium-derived EA.hy926 cells.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable