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Key Documents

295167

Sigma-Aldrich

Chlorotrifluoroethylene

98%

Synonym(s):

CTFE

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About This Item

Linear Formula:
ClCF=CF2
CAS Number:
Molecular Weight:
116.47
EC Number:
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:

vapor density

4.13 (vs air)

Assay

98%

contains

1% tributylamine as inhibitor

bp

−28.4 °C (lit.)

mp

−158 °C (lit.)

SMILES string

F\C(F)=C(\F)Cl

InChI

1S/C2ClF3/c3-1(4)2(5)6

InChI key

UUAGAQFQZIEFAH-UHFFFAOYSA-N

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Packaging

Supplied in a Sure/Pac cylinder and has a 316 stainless steel diaphragm valve with a male 1/4" NPTF outlet thread (Z168637) installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.

Compatible with the following:

Legal Information

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Gas 1 - Press. Gas Liquefied gas

Storage Class Code

2A - Gases

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M Rahman et al.
Journal of applied toxicology : JAT, 14(1), 43-46 (1994-01-01)
The effect of isoflurane on the anaerobic metabolism of halothane to chlorodifluoroethene (CDE) and chlorotrifluoroethane (CTE) was studied with microsomes of guinea pig liver by gas chromatography. The reaction mixture used to measure the end products of anaerobic metabolism consisted
P J Boogaard et al.
Biochemical pharmacology, 39(8), 1335-1345 (1990-04-15)
The aim of this study was to set up an in vitro system to study nephrotoxicity of xenobiotics which allows exposure at low concentrations for long periods (1-5 days). A very pure preparation of isolated proximal tubular cells (PTC) from
M J Diaz et al.
Biochemical pharmacology, 46(6), 1076-1080 (1993-09-14)
Male Wistar albino rats were treated for a 7 day period with equimolar doses of the trimer and tetramer oligomers of chlorotrifluoroethylene (CTFE), resulting in significant hepatomegaly for both compounds. In addition, both trimer and tetramer significantly induced the peroxisomal
C D Hassall et al.
Chemico-biological interactions, 49(3), 283-297 (1984-05-01)
The nephrotoxicity of chlorotrifluoroethylene ( CTFE ) was examined using isolated rabbit renal tubules suspensions. Exposure of the tubules to CTFE resulted in consumption of CTFE , formation of a glutathione conjugate and inhibition of active organic acid transport. Synthetic
J W Harris et al.
Chemical research in toxicology, 5(1), 34-41 (1992-01-01)
Several haloalkenes are selective nephrotoxins. The bioactivation of nephrotoxic haloalkenes involves hepatic glutathione S-conjugate formation, peptidase-catalyzed metabolism of the glutathione S-conjugates to the corresponding cysteine S-conjugates, uptake of cysteine S-conjugates by the kidneys, and renal cysteine conjugate beta-lyase-catalyzed beta-elimination of

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