XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
Synonyms:
Species:
Human XRCC4 (7518), Mouse Xrcc4 (108138), Rat Xrcc4 (309995), chicken XRCC4 (427325), dog XRCC4 (488923), Zebrafish xrcc4 (393759), domestic guinea pig Xrcc4 (100731158), sheep XRCC4 (101102481), naked mole-rat Xrcc4 (101709691), cow XRCC4 (613590)
UniProtKB ID:
Gene ID:
- Human(7518) Summary: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008]
- Mouse(108138) X-ray repair complementing defective repair in Chinese hamster cells 4
- Rat(309995) X-ray repair complementing defective repair in Chinese hamster cells 4
- chicken(427325) X-ray repair complementing defective repair in Chinese hamster cells 4
- dog(488923) X-ray repair complementing defective repair in Chinese hamster cells 4
- Zebrafish(393759) X-ray repair complementing defective repair in Chinese hamster cells 4
- domestic guinea pig(100731158) X-ray repair complementing defective repair in Chinese hamster cells 4
- sheep(101102481) X-ray repair complementing defective repair in Chinese hamster cells 4
- naked mole-rat(101709691) X-ray repair complementing defective repair in Chinese hamster cells 4
- cow(613590) X-ray repair complementing defective repair in Chinese hamster cells 4
- Thale Cress(821885) DNA repair protein XRCC4-like protein
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-XRCC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-XRCC4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-XRCC4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-XRCC4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-XRCC4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence