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Merck

SRY

sex determining region Y

Synonyms:
SRXX1, SRXY1, TDF, TDY
Species:
Human SRY (6736), Mouse Sry (21674), Rat Sry (25221), domestic cat SRY (493758), cow SRY (280931), Horse SRY (100033824), sheep SRY (100529253), Domestic Rabbit SRY (100328958)
UniProtKB ID:
Q05066
Gene ID:
  • Human(6736) Summary: This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(21674) sex determining region of Chr Y
  • Rat(25221) sex determining region Y
  • domestic cat(493758) sex determining region Y
  • cow(280931) sex determining region Y
  • Horse(100033824) sex determining region Y
  • sheep(100529253) sex determining region Y
  • Domestic Rabbit(100328958) sex determining region Y

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
MABN1101
Anti-SRY, clone 1G4 Antibody, clone 1G4, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
western blot
07-1673
Anti-SOX1 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunohistochemistry
HPA073666
Anti-SRI antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
HPA019004
Anti-SRI antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
WH0006717M1
Monoclonal Anti-SRI antibody produced in mouse, clone 1E12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
EHU002121
MISSION® esiRNA, targeting human SRY,
Species
human
EMU035211
MISSION® esiRNA, targeting mouse Sri,
Species
mouse
EHU079901
MISSION® esiRNA, targeting human SRI,
Species
human