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Merck

PCK1

phosphoenolpyruvate carboxykinase 1 (soluble)

Synonyms:
PEPCK-C, PEPCK1, PEPCKC
Species:
UniProtKB ID:
Gene ID:
  • Human(5105) Summary: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(18534) phosphoenolpyruvate carboxykinase 1, cytosolic
  • Rat(362282) phosphoenolpyruvate carboxykinase 1 (soluble)
  • domestic guinea pig(100724258) phosphoenolpyruvate carboxykinase 1 (soluble)
  • Domestic Rabbit(100355682) phosphoenolpyruvate carboxykinase 1 (soluble)
  • cow(282855) phosphoenolpyruvate carboxykinase 1 (soluble)
  • sheep(100037690) phosphoenolpyruvate carboxykinase 1 (soluble)
  • sheep(101117351) phosphoenolpyruvate carboxykinase 1 (soluble)
  • chicken(396458) phosphoenolpyruvate carboxykinase 1 (soluble)
  • domestic cat(101089256) phosphoenolpyruvate carboxykinase 1 (soluble)
  • Zebrafish(378727) phosphoenolpyruvate carboxykinase 1 (soluble)
  • Thale Cress(829943) phosphoenolpyruvate carboxykinase [ATP]
  • dog(403560) phosphoenolpyruvate carboxykinase 1 (soluble)
  • naked mole-rat(101708730) phosphoenolpyruvate carboxykinase 1 (soluble)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PCK1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, rat
Application
western blot
Anti-PCK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PCK1 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-PCK1 Mouse mAb (3E4), liquid, clone 3E4, Calbiochem®,
Species Reactivity
human
Application
Anti-PCK1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PCK1,
Species
human