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Merck

LOXL2

lysyl oxidase-like 2

Synonyms:
LOR2, WS9-14
Species:
UniProtKB ID:
Gene ID:
  • Human(4017) Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
  • Mouse(94352) lysyl oxidase-like 2
  • Rat(290350) lysyl oxidase-like 2
  • domestic guinea pig(100729973) lysyl oxidase-like 2
  • chicken(419533) lysyl oxidase-like 2
  • domestic cat(101084102) lysyl oxidase-like 2
  • dog(486118) lysyl oxidase-like 2
  • cow(532684) lysyl oxidase-like 2
  • Domestic Rabbit(100346678) lysyl oxidase-like 2
  • sheep(101120812) lysyl oxidase-like 2
  • naked mole-rat(101700042) lysyl oxidase-like 2

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LOXL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-LOXL2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-LOXL2 Antibody, clone GS341, ,
Species Reactivity
human, mouse
Application
ELISA
inhibition assay

western blot
Anti-LOXL2, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-LOXL2, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

Product Number
Description
Species
LOXL2 human, recombinant, expressed in FreeStyle 293-F cells, ≥86% (SDS-PAGE),
Species
human
Lysyl Oxidase-like 2 (LOXL2) FLAG-tag (Sf9-derived) human, recombinant, expressed in baculovirus infected insect cells, ≥65% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LOXL2,
Species
human
MISSION® esiRNA, targeting mouse Loxl2,
Species
mouse